Abstract Background Computed tomographic pulmonary angiography (CTPA) is the diagnostic standard for confirming pulmonary embolism (PE).Since PE is a life-threatening condition, early diagnosis and treatment are critical to avoid PE-associated morbidity and mortality.However, PE remains subject to misdiagnosis.Methods We retrospectively identified
The scientific community is growing increasingly aware of the importance of the FAIR data management principles for publishing scientific data.For data providers, this includes creating machine-understandable file structures such as CF-NetCDF files and Darwin Core Archives.To support scientists in creating these, we present significant upgrades to
In recent studies, vapour transfer is reported to lead to remarkable frost heave in unsaturated soils, but how to better model this process has not been answered.In order to avoid bald ass dog the great uncertainty caused by the phase change term of vapour-water-ice in the numerical iteration process, a new numerical model is developed based on the
BackgroundMalignant melanoma is an extremely aggressive and metastatic cancer, and highly resistant to conventional therapies.Signal transducer and activator of transcription 3 (STAT3) signaling promotes melanoma development and progression, which has been validated as an effective target in melanoma treatment.Natural naphthoquinone shikonin is rep
Ammonium (NH4+) is one of the major nitrogen sources for plants.However, excessive ammonium can cause serious harm to the growth and development of plants, i.e., ammonium toxicity.The primary regulatory mechanisms behind ammonium toxicity are still poorly characterized.In this study, we showed that OsCIPK18, a CBL-interacting protein kinase, plays